Factor Seven Activating Protease » Reviews http://www.factor-seven-activating-protease.com Information on FSAP Fri, 20 Aug 2010 07:45:08 +0000 http://wordpress.org/?v=2.9.2 en hourly 1 Review on the possible role of FSAP in coagulation, fibrinolysis and atherothrombosis http://www.factor-seven-activating-protease.com/review-on-the-possible-role-of-fsap-in-coagulation-fibrinolysis-and-atherothrombosis/ http://www.factor-seven-activating-protease.com/review-on-the-possible-role-of-fsap-in-coagulation-fibrinolysis-and-atherothrombosis/#comments Mon, 22 Jun 2009 17:35:48 +0000 admin http://www.factor-seven-activating-protease.com/?p=119 In this 2003 editorial Mann discusses the biological role of FSAP. He points out that 1 % of total plasma factor VII is present in its cleaved enzymatically active form (VIIa) and that so far there is no adequate explanation for the source of this active enzyme.

He suggests that “… FSAP is a leading candidate for the maintenance of plasma factor VIIa, and its evaluation may prove useful.”

He continues that FSAP “…. provides an additional linkage between the initiation of the coagulation system and fibrinolysis…”.

Author and Source:
Mann, Circulation. 2003 Feb 11;107(5):654-655

Title:
Factor VII-activating protease: coagulation, fibrinolysis, and atherothrombosis?

]]> http://www.factor-seven-activating-protease.com/review-on-the-possible-role-of-fsap-in-coagulation-fibrinolysis-and-atherothrombosis/feed/ 0 Tests for Factor VII-Activating Protease http://www.factor-seven-activating-protease.com/tests-for-factor-seven-activating-protease/ http://www.factor-seven-activating-protease.com/tests-for-factor-seven-activating-protease/#comments Tue, 26 May 2009 08:10:00 +0000 admin http://www.factor-seven-activating-protease.com/?p=114 Stephan and colleagues review and summarize information on different assays for FSAP and its Marburg I variant. This includes the measurement of antigen levels, pro-uPA and FVII activating activity, and genotype.

Authors and Source:
Stephan et al., Clin Chem Lab Med. 2008;46(8):1109-1116.

Title:
Tests for the measurement of factor VII-activating protease (FSAP) activity and antigen levels in citrated plasma, their correlation to PCR testing, and utility for the detection of the Marburg I-polymorphism of FSAP

]]> http://www.factor-seven-activating-protease.com/tests-for-factor-seven-activating-protease/feed/ 0 Review on Factor VII-Activating Protease and Atherosclerosis http://www.factor-seven-activating-protease.com/review-on-factor-seven-activating-protease-and-atherosclerosis/ http://www.factor-seven-activating-protease.com/review-on-factor-seven-activating-protease-and-atherosclerosis/#comments Mon, 25 May 2009 21:37:12 +0000 admin http://www.factor-seven-activating-protease.com/?p=108 This is a current review on the role of FSAP in vascular biology, i.e. the “… contribution of FSAP to vascular fibroproliferative inflammatory diseases in the context of pericellular proteolysis of the extracellular matrix, growth factor activity and hemostasis …”.

Authors and Source:
Kanse et al., Thromb Haemost. 2008 Feb;99(2):286-289.

Title:
Factor VII-activating protease (FSAP): vascular functions and role in atherosclerosis

]]> http://www.factor-seven-activating-protease.com/review-on-factor-seven-activating-protease-and-atherosclerosis/feed/ 0